๐”– Bobbio Scriptorium
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Regulation of megakaryocyte maturation and platelet formation

โœ Scribed by D. BLUTEAU; L. LORDIER; A. DI STEFANO; Y. CHANG; H. RASLOVA; N. DEBILI; W. VAINCHENKER

Book ID
114754539
Publisher
John Wiley and Sons
Year
2009
Tongue
English
Weight
335 KB
Volume
7
Category
Article
ISSN
1538-7933

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## Abstract Recent data suggest that megakaryocytes (MKs) play a role in skeletal homeostasis. In vitro and in vivo data show that MKs stimulate osteoblast (OB) proliferation and inhibit osteoclast (OC) formation, thus favoring net bone deposition. There are several mouse models with dysregulated m