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Regulation of K channels in cardiac myocytes by free fatty acids: A mechanism of K loss in ischemia

✍ Scribed by Donghee Kim; Richard A. Duff

Book ID
115981611
Publisher
Elsevier Science
Year
1990
Tongue
English
Weight
97 KB
Volume
22
Category
Article
ISSN
0022-2828

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The effects of fatty acids on voltage-dependent potassium (K Β§ channels in neuroblastoma cells were studied using the whole-cell current recording technique. At a concentration of 5 ~tM, unsaturated and medium chain length (C10-C14) saturated fatty acids accelerated the apparent inactivation of the