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On the molecular regulation of muscarinic K+ channels by acetylcholine in cardiac cell membrane

โœ Scribed by Kurachi, Yoshihisa


Book ID
122470090
Publisher
Elsevier Science
Year
1988
Weight
64 KB
Volume
7
Category
Article
ISSN
0921-8696

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Positive cooperativity in activation of
โœ Yoshihisa Kurachi; Hiroyuki Ito; Tsuneaki Sugimoto ๐Ÿ“‚ Article ๐Ÿ“… 1990 ๐Ÿ› Springer ๐ŸŒ English โš– 232 KB

Concentration-dependent effects of intracellular GTP on activation of the muscarinic K + channel were examined in inside-out patches of cardiac atrial myocytes. The pipette solution contained 0.i ~I ACh. GTP (0.01-30 ~M) and 0.5 mM MgCI 2 were applied to the inside side of the patch membrane. K + ch