𝔖 Bobbio Scriptorium
✦   LIBER   ✦

Regulation of JAK2 Activation by Janus Homology 2: Evidence from Molecular Dynamics Simulations

✍ Scribed by Wan, Shunzhou; Coveney, Peter V.


Book ID
115509824
Publisher
American Chemical Society
Year
2012
Tongue
English
Weight
667 KB
Volume
52
Category
Article
ISSN
0095-2338

No coin nor oath required. For personal study only.


πŸ“œ SIMILAR VOLUMES


Mechanisms of constitutive activation of
✍ Tai-Sung Lee; Wanlong Ma; Xi Zhang; Francis Giles; Hagop Kantarjian; Maher Albit πŸ“‚ Article πŸ“… 2009 πŸ› John Wiley and Sons 🌐 English βš– 911 KB

## Abstract ## BACKGROUND: The tyrosine kinase Janus kinase 2 (JAK2) is important in triggering nuclear translocation and regulation of target genes expression through signal transducer and activator of transcription pathways. The valine‐to‐phenylalanine mutation at amino acid 617 (V617F), which r