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Regulation of inducible no synthase expression by endothelin in primary cultured glial cells

โœ Scribed by Toshihiko Murayama; Haruko Oda; Yukio Sasaki; Toshikazu Okada; Yasuyuki Nomura


Book ID
117175609
Publisher
Elsevier Science
Year
1998
Tongue
English
Weight
360 KB
Volume
62
Category
Article
ISSN
0024-3205

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Lipopolysaccharide (LPS) or a combination of interleukin (IL)-lp and interferon (1FN)-y cause transcriptional induction of a calcium-independent nitric oxide synthase (NOS) in astrocytes and C6 glioma cells. LPS induction of NOS in C6 cells was evidenced by a small amount of nitrite accumulation as