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Regulation of hepatic CYP1A isozymes by piperonyl butoxide and acenaphthylene in the mouse

✍ Scribed by Doug-Young Ryu; Patricia E Levi; Ernest Hodgson

Book ID: 114009442
Publisher: Elsevier Science
Year: 1997
Tongue: English
Weight: 360 KB
Volume: 105
Category: Article
ISSN: 0009-2797
DOI: 10.1016/s0009-2797(97)00035-5

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## Abstract __CYP11A1__ encodes the first enzyme of steroid biosynthesis, cytochrome P450scc. The expression of __CYP11A1__ in the nervous system allows neurosteroids to be synthesized de novo. In the classic steroidogenic tissues, adrenals and gonads, the key regulator controlling __CYP11A1__ expr