Ontogeny of hepatic CYP1A2 and CYP2E1 ex
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Fawzy A. Elbarbry; Patrick J. McNamara; Jane Alcorn
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Article
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2007
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John Wiley and Sons
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English
β 404 KB
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## Abstract We report a comprehensive examination of rat hepatic CYP1A2 and CYP2E1 ontogeny. We compare the data to human data to determine the rat's capacity as a model to identify CYPβmediated mechanisms underlying ageβdependent differences in susceptibility to toxicity. We evaluated CYP expressi