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Regulation of growth of normal ovarian epithelium and ovarian cancer cell lines by transforming growth factor-β

✍ Scribed by A. Berchuck; G. Rodriguez; G. Olt; B. Arrick; D.L. Clarke-Pearson; R.C. Bast Jr.


Book ID
119053885
Publisher
Elsevier Science
Year
1991
Tongue
English
Weight
158 KB
Volume
40
Category
Article
ISSN
0090-8258

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## Abstract Our study demonstrates that quercetin (Q)‐induced growth‐inhibitory activity in ovarian cancer cells may be mediated by modulation of transforming growth factor β~1~ (TGFβ~1~) production. We used the OVCA 433 cell line which is very sensitive to the anti‐proliferative effect of Q and ex