Transforming growth factor-beta (TGF-P) is a polypeptide with multiple physiological functions. lsoforms of this growth factor have important roles in control of the cell cycle, in regulation of cell-cell interactions and in growth and development. Malignant transformation has been shown to be assoc
Expression and action of transforming growth factor beta (TGFβ1, TGFβ2, TGFβ3) in normal bovine ovarian surface epithelium and implications for human ovarian cancer
✍ Scribed by Eric Nilsson; Vinayak Doraiswamy; Jeff A. Parrott; Michael K. Skinner
- Book ID
- 117462843
- Publisher
- Elsevier Science
- Year
- 2001
- Tongue
- English
- Weight
- 401 KB
- Volume
- 182
- Category
- Article
- ISSN
- 0303-7207
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Transforming growth factor-b (TGF-b1) is a potent negative regulator of cell growth that transduces signals through interactions with type I and II receptors. Abnormal expression and mutational alterations of these receptors have been observed in several human malignancies. In this study, we investi