## Abstract HS3, a highly phosphorylated dinucleoside originally purified from the fungus __Achlya__, has been isolated from Chinese hamster ovary cells undergoing glutamine starvation. The HS3 compounds obtained from the fungal and mammalian sources exhibited similar physical and chemical properti
✦ LIBER ✦
Regulation of fungal ribonucleotide reductase by unusual dinucleotides
✍ Scribed by William H. Lewis; David R. McNaughton; Herb B. LéJohn; Jim A. Wright
- Book ID
- 118310548
- Publisher
- Elsevier Science
- Year
- 1976
- Tongue
- English
- Weight
- 499 KB
- Volume
- 71
- Category
- Article
- ISSN
- 0006-291X
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Mammalian ribonucleotide reductase catalyzes the rate-limiting for the de novo synthesis 2'-deoxyribonucleoside 5'-triphosphates. There is some suggestion that this step may also be the rate-limiting step of DNA synthesis. It is apparent that the level of the enzyme, ribonucleotide reductase, varies