Regulation of ribonucleotide reductase a
β
Joseph G. Cory; Atsushi Sato
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Article
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1983
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Springer
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English
β 832 KB
Mammalian ribonucleotide reductase catalyzes the rate-limiting for the de novo synthesis 2'-deoxyribonucleoside 5'-triphosphates. There is some suggestion that this step may also be the rate-limiting step of DNA synthesis. It is apparent that the level of the enzyme, ribonucleotide reductase, varies