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Regulation of folliculin (the BHD gene product) phosphorylation by Tsc2-mTOR pathway

โœ Scribed by Xianghua Piao; Toshiyuki Kobayashi; Lu Wang; Masatoshi Shiono; Yumiko Takagi; Guodong Sun; Masaaki Abe; Yoshiaki Hagiwara; Danqing Zhang; Kazuo Okimoto; Mami Kouchi; Izumi Matsumoto; Okio Hino


Book ID
116299090
Publisher
Elsevier Science
Year
2009
Tongue
English
Weight
623 KB
Volume
389
Category
Article
ISSN
0006-291X

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โœ L. Kern; J. Montigny; F. Lacroute; R. Jund ๐Ÿ“‚ Article ๐Ÿ“… 1991 ๐Ÿ› Springer-Verlag ๐ŸŒ English โš– 471 KB

In Saccharomyces cerevisiae, the protein encoded by the FUR1 gene is absolutely required for the expression of uracil phosphoribosyl transferase activity. The occurrence of semi-dominant mutations for 5-fluorouracil-(5FU)-resistance at this locus led us to clone and sequence the semi-dominant fur1-5