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Regulation of DNA synthesis in cytochalasin B (CB)-induced binucleate HeLa cells

✍ Scribed by P.N. Rao; Marion L. Smith


Book ID
118876882
Publisher
Elsevier Science
Year
1976
Tongue
English
Weight
449 KB
Volume
103
Category
Article
ISSN
0014-4827

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## Abstract Cytochalasin B influences a variety of cellular events that are associated with the contractile microfilament system and the formation of binucleate cells. Along with the formation of binucleate cells, cytochalasin B also causes an acceleration of cells from G~1~ to S in the cell cycle

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## Abstract Cytochalasin B was used as a tool to study the inter‐relationships between cell movement, the reinitiated DNA synthesis and the enhanced transport of specific small molecules stimulated by serum in quiescent 3T3 cells. Cytochalasin at concentrations of less than 1 ΞΌg/ml inhibits serum‐s