After a shift from a nonpermissive to a permissive temperature, synchronized DNA synthesis and cell division were observed in a cold-sensitive anchorageindependent growth mutant (cs-17-25) of Chinese hamster lung cells in Methocel culture. Only 15 rnin exposure to the permissive temperature was suff
Inhibition of DNA Synthesis in Adrenocortical Cells by Cytochalasin B
β Scribed by M. A. McPherson and J. Ramachandran
- Book ID
- 124799395
- Publisher
- Rockefeller University Press.
- Year
- 1980
- Tongue
- English
- Weight
- 301 KB
- Volume
- 86
- Category
- Article
- ISSN
- 0021-9525
- DOI
- 10.2307/1609080
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## Abstract Cytochalasin B influences a variety of cellular events that are associated with the contractile microfilament system and the formation of binucleate cells. Along with the formation of binucleate cells, cytochalasin B also causes an acceleration of cells from G~1~ to S in the cell cycle
## Abstract Cytochalasin B was used as a tool to study the interβrelationships between cell movement, the reinitiated DNA synthesis and the enhanced transport of specific small molecules stimulated by serum in quiescent 3T3 cells. Cytochalasin at concentrations of less than 1 ΞΌg/ml inhibits serumβs