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Regulation of CD95/APO-1/Fas-induced apoptosis by protein phosphatases

✍ Scribed by Geoffrey Gloire; Edith Charlier; Jacques Piette

Book ID
113488564
Publisher
Elsevier Science
Year
2008
Tongue
English
Weight
450 KB
Volume
76
Category
Article
ISSN
0006-2952

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✍ Marcus E Peter; Peter H Krammer πŸ“‚ Article πŸ“… 1998 πŸ› Elsevier Science 🌐 English βš– 725 KB

This review covers recent advances of CD95 signaling. It focuses on CD95-interacting molecules, formation of the death inducing signaling complex and the role of caspases, particularly caspase-8, and their death substrates. We also discuss the relevance of mitochondria in the CDg5-mediated apoptotic