Mechanisms of CD95 (APO-1/Fas)-mediated
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Marcus E Peter; Peter H Krammer
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Article
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1998
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Elsevier Science
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English
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This review covers recent advances of CD95 signaling. It focuses on CD95-interacting molecules, formation of the death inducing signaling complex and the role of caspases, particularly caspase-8, and their death substrates. We also discuss the relevance of mitochondria in the CDg5-mediated apoptotic