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Regulation of CD8+ T Cell Development by Thymus-Specific Proteasomes

✍ Scribed by Murata, S.; Sasaki, K.; Kishimoto, T.; Niwa, S.-i.; Hayashi, H.; Takahama, Y.; Tanaka, K.

Book ID
121746151
Publisher
American Association for the Advancement of Science
Year
2007
Tongue
English
Weight
436 KB
Volume
316
Category
Article
ISSN
0036-8075

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Recent findings suggest that mature T cells in the thymus may regulate the growth and differentiation of immature thymocytes. Here we use mathematical modeling and computer simulations to identify the thymocyte subsets that might serve as targets for regulation, and the processes that might be affec