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Regulation of CD2-Mediated Human T Cell Activation: Anti-CD8 Monoclonal Antibodies Inhibit CD2-Mediated Rise in Intracellular Calcium

✍ Scribed by Marie-Dominique Franco; Jacques Nunes; Carol Lipcey; Marc Lopez; Claude Mawas; Daniel Olive


Book ID
112238800
Publisher
Elsevier Science
Year
1993
Tongue
English
Weight
479 KB
Volume
152
Category
Article
ISSN
0008-8749

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Monoclonal antibodies (mAb) directed against the T cell differentiation antigen CD28 (Tp44) induce proliferation of resting T lymphocytes in the presence of phorbol esters. Moreover, it has been reported that such antibodies augment and sustain T cell proliferation induced by soluble antigens, phyto