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Intracellular calcium levels are differentially regulated in T lymphocytes triggered by anti-CD2 and anti-CD3 monoclonal antibodies

โœ Scribed by Fabrizio Spinozzi; Elisabetta Agea; Onelia Bistoni; Silvia Belia; Annamaria Travetti; Roberto Gerli; Christopher Muscat; Alberto Bertotto


Book ID
113388625
Publisher
Elsevier Science
Year
1995
Tongue
English
Weight
454 KB
Volume
7
Category
Article
ISSN
0898-6568

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The proliferation of autologous tumor-reactive cytotoxic T lymphocytes (CTL), induced by autologous mixed lymphocyte tumor-cell culture, was remarkably enhanced by activation with immobilized anti-CD3 monoclonal antibody (MAb) and interleukin-2 (IL-2), as compared with IL-2 alone. The activated CTL