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Monoclonal Anti-CD44 Antibody Acts in Synergy with Anti-CD2 but Inhibits Anti-CD3 or T Cell Receptor-Mediated Signaling in Murine T Cell Hybridomas

✍ Scribed by Ya-Jun Guo; Jing Ma; Jin-Hong Wong; Shih-Chang Lin; Hsiu-Ching Chang; Michael Bigby; Man-Sun Sy


Book ID
112238802
Publisher
Elsevier Science
Year
1993
Tongue
English
Weight
465 KB
Volume
152
Category
Article
ISSN
0008-8749

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Monoclonal antibodies (mAb) directed against the T cell differentiation antigen CD28 (Tp44) induce proliferation of resting T lymphocytes in the presence of phorbol esters. Moreover, it has been reported that such antibodies augment and sustain T cell proliferation induced by soluble antigens, phyto