Regulation of Apoptosis by Adenovirus E1A and E1B Oncogenes
โ Scribed by Eileen White
- Book ID
- 118771136
- Publisher
- Elsevier Science
- Year
- 1998
- Tongue
- English
- Weight
- 107 KB
- Volume
- 8
- Category
- Article
- ISSN
- 1044-5773
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๐ SIMILAR VOLUMES
We have isolated a revertant cell line (G5) from an adenovirus transformed rat cell line (F4) which failed to express the integrated viral oncogenes. To determine whether the reversion mutation was acting in cis or trans the G5 cells were co-transfected with an El gene bearing expression plasmid and
Cancer is usually envisioned as a disease of cellular proliferation. That is, loss of controls on cell proliferation is viewed as being the central, underlying cause of cancer. Recently, however, this idea has undergone a change. With the realization that cell number is a result of the competing eff