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Adenovirus E1A negatively regulates E1AF, an ets family of the protein

✍ Scribed by Akiko Takahashi; Fumihiro Higashino; Mariko Aoyagi; Masayuki Nakayama; Aya Yanagawa; Hiroichi Hasegawa; Mitsutoki Hatta; Setsuko Ishida; Koichi Nakajima; Yasunori Totsuka; Masanobu Shindoh


Book ID
116294421
Publisher
Elsevier Science
Year
2007
Tongue
English
Weight
144 KB
Volume
355
Category
Article
ISSN
0006-291X

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The epidermal growth factor receptor (EGF-R), after activation by its ligands, stimulates a cascade of intracellular events leading to cellular proliferation. Its expression is increased in various forms of cancer as a consequence of altered regulation. Our objective was to study potential negative