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Regulation of 25-hydroxyvitamin d-1α-hydroxylase by IFNγ in human monocytic THP1 cells

✍ Scribed by Lut Overbergh; Katinka Stoffels; Dirk Valckx; Annapaula Giulietti; Roger Bouillon; Chantal Mathieu

Book ID
116697316
Publisher
Elsevier Science
Year
2004
Tongue
English
Weight
92 KB
Volume
89-90
Category
Article
ISSN
0960-0760

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## Abstract In monocytes and macrophages, activation of the tyrosine kinase Syk is an essential step in the biochemical cascade linking aggregation of receptors for immunoglobulin G (FcγR) to initiation of effector functions. An increase in Syk activation during differentiation of myeloid cells by