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Hormonal regulation of 25-hydroxyvitamin D3-1α-hydroxylase and 24-hydroxylase gene transcription in opossum kidney cells

✍ Scribed by H.J Armbrecht; T.L Hodam; M.A Boltz

Book ID
117042358
Publisher
Elsevier Science
Year
2003
Tongue
English
Weight
190 KB
Volume
409
Category
Article
ISSN
0003-9861

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✍ Claudia Zierold; Jamie A. Mings; Hector F. DeLuca 📂 Article 📅 2002 🏛 John Wiley and Sons 🌐 English ⚖ 100 KB

## Abstract The 25‐hydroxyvitamin D~3~‐24‐hydroxylase mRNA is tightly and reciprocally regulated by 1,25‐dihydroxyvitamin D~3~ (1,25(OH)~2~D~3~) and parathyroid hormone (PTH). The upregulation of the 24‐hydroxylase by 1,25(OH)~2~D~3~ is well established and occurs at the transcriptional level throu