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Distribution and regulation of the 25-hydroxyvitamin D3 1α-hydroxylase in human parathyroid glands

✍ Scribed by Cynthia S. Ritter; Bruce H. Haughey; Harvey J. Armbrecht; Alex J. Brown

Book ID
116698768
Publisher
Elsevier Science
Year
2012
Tongue
English
Weight
1005 KB
Volume
130
Category
Article
ISSN
0960-0760

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## Abstract The 25‐hydroxyvitamin D~3~‐24‐hydroxylase mRNA is tightly and reciprocally regulated by 1,25‐dihydroxyvitamin D~3~ (1,25(OH)~2~D~3~) and parathyroid hormone (PTH). The upregulation of the 24‐hydroxylase by 1,25(OH)~2~D~3~ is well established and occurs at the transcriptional level throu