Regulation, cellular localization, and function of the p75 neurotrophin receptor (p75NTR) during the regeneration of facial motoneurons
β Scribed by Andreas Gschwendtner; ZhiQiang Liu; Tim Hucho; Marion Bohatschek; Roger Kalla; Georg Dechant; Gennadij Raivich
- Book ID
- 117701516
- Publisher
- Elsevier Science
- Year
- 2003
- Tongue
- English
- Weight
- 949 KB
- Volume
- 24
- Category
- Article
- ISSN
- 1044-7431
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When motoneuron axons in periph-{ standard error of the mean 3%, n Γ 11 vs. 67 { 5%, eral nerves are injured, the expression of the p75 lown Γ 11 in CD-1 mice and 68.0 { 4%, n Γ 6 in balb/ affinity neurotrophin receptor (p75) increases in their c mice), and significantly more regenerating axons cell
## Abstract The common neurotrophin receptor (p75^NTR^) regulates various functions in the developing and adult nervous system. Cell survival, cell death, axonal and growth cone retraction, and regulation of the cell cycle can be regulated by p75^NTR^βmediated signals following activation by either