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Regulated trafficking of the CFTR chloride channel

โœ Scribed by Bertrand Kleizen; Ineke Braakman; Hugo R. de Jonge

Book ID
114493078
Publisher
Elsevier Science
Year
2000
Tongue
English
Weight
294 KB
Volume
79
Category
Article
ISSN
0171-9335

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The cystic fibrosis transmembrane conductance regulator (CFTR) is an ATP-dependent channel which mediates CAMP-stimulated chloride secretion by epithelia, particularly those of the pancreas, airways, and intestine. CFTR homologues have been found in all higher vertebrates examined to date and also i