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Regulation of CFTR chloride channels by syntaxin and Munc18 isoforms

โœ Scribed by Kirk, Kevin L.; Naren, Anjaparavanda P.; Nelson, Deborah J.; Xie, Weiwen; Jovov, Biljana; Pevsner, Jonathan; Bennett, Mark K.; Benos, Dale J.; Quick, Michael W.

Book ID
109788399
Publisher
Nature Publishing Group
Year
1997
Tongue
English
Weight
411 KB
Volume
390
Category
Article
ISSN
0028-0836

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The cystic fibrosis transmembrane conductance regulator (CFTR) is an ATP-dependent channel which mediates CAMP-stimulated chloride secretion by epithelia, particularly those of the pancreas, airways, and intestine. CFTR homologues have been found in all higher vertebrates examined to date and also i