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CFTR: A chloride channel, channel regulator, or both?

โœ Scribed by Rossier, Bernard


Book ID
104474698
Publisher
Nature Publishing Group
Year
2002
Tongue
English
Weight
52 KB
Volume
62
Category
Article
ISSN
0085-2538

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The cystic fibrosis transmembrane conductance regulator (CFTR) is an ATP-dependent channel which mediates CAMP-stimulated chloride secretion by epithelia, particularly those of the pancreas, airways, and intestine. CFTR homologues have been found in all higher vertebrates examined to date and also i