Regiospecific synthesis of α-ketoacetals by rearrangement of α-bromo-α-fluoroketones
✍ Scribed by Norbert De Kimpe; Roland Verhé; Laurent De Buyck; N. Schamp
- Publisher
- Elsevier Science
- Year
- 1980
- Tongue
- French
- Weight
- 234 KB
- Volume
- 21
- Category
- Article
- ISSN
- 0040-4039
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📜 SIMILAR VOLUMES
Treatment of pyruvate ketal-derived diazoacetoacetates or vinyldiazoketones with rhodium(II) complexes at elevated temperatures results in an unusual skeletal rearrangement to afford eight-membered ring lactones.
AbstractÐA convenient synthesis of a-diones and their monoprotected acetals, i.e. a-ketoacetals, was developed by mercury induced solvolysis of regiospeci®cally formed a-chloro-a-(alkylthio)ketones. Analogously, a-alkoxy-a-sulfenylated ketones were formed when reacting a-chloro-a-sulfenylated ketone
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