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Regioselective synthesis of fused pyrazolo[1,5-a]pyrimidines by reaction of 5-amino-1H-pyrazoles and β-dicarbonyl compounds containing five-membered rings

✍ Scribed by Jaime Portilla; Jairo Quiroga; Manuel Nogueras; Justo Cobo


Book ID
113929184
Publisher
Elsevier Science
Year
2012
Tongue
French
Weight
415 KB
Volume
68
Category
Article
ISSN
0040-4020

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Synthesis of 6-(2-hydroxybenzoyl)pyrazol
✍ Jairo Quiroga; Diana Mejía; Braulio Insuasty; Rodrigo Abonía; Manuel Nogueras; A 📂 Article 📅 2002 🏛 Journal of Heterocyclic Chemistry 🌐 English ⚖ 41 KB

## Abstract Reaction of 3‐formylchromone (**1**) with 5‐amino‐1__H__‐pyrazoles (**2**) in ethanol, afforded 6‐(2‐hydroxy‐benzoyl)pyrazolo[1,5‐__a__]pyrimidines (**3a‐g**) in good yields. The structures and the regiospecificity of the reaction were established by nmr measurements and X‐ray analysis,