## Abstract Reaction of 3‐formylchromone (**1**) with 5‐amino‐1__H__‐pyrazoles (**2**) in ethanol, afforded 6‐(2‐hydroxy‐benzoyl)pyrazolo[1,5‐__a__]pyrimidines (**3a‐g**) in good yields. The structures and the regiospecificity of the reaction were established by nmr measurements and X‐ray analysis,
ChemInform Abstract: Synthesis of 6-(2-Hydroxybenzoyl)pyrazolo[1,5-a]pyrimidines by Reaction of 5-Amino-1H-pyrazoles and 3-Formylchromone.
✍ Scribed by Jairo Quiroga; Diana Mejia; Braulio Insuasty; Rodrigo Abonia; Manuel Nogueras; Adolfo Sanchez; Justo Cobo; J. N. Low
- Publisher
- John Wiley and Sons
- Year
- 2010
- Weight
- 31 KB
- Volume
- 33
- Category
- Article
- ISSN
- 0931-7597
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📜 SIMILAR VOLUMES
## Abstract A convenient four‐step synthesis of the aminobicyclopyrazolone hydrochloride **1**·HC1 was achieved starting from di‐__tert__‐butyl hydrazodiformate **(8)**. The route entails cyclization of **8** with 1,3‐dibromopropane under phase transfer conditions followed by deprotection of 1,2‐di
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