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Regioselective Michael addition of thiols to tertiary fumaric amide esters

✍ Scribed by Akio Kamimura; Norikazu Murakami; Kakuteru Yokota; Masashi Shirai; Hiroaki Okamoto

Book ID: 104252075
Publisher: Elsevier Science
Year: 2002
Tongue: French
Weight: 145 KB
Volume: 43
Category: Article
ISSN: 0040-4039
DOI: 10.1016/s0040-4039(02)01824-5

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✦ Synopsis

The regiochemistry of the Michael addition of thiols to tertiary fumaric amide esters was efficiently controlled in the presence or absence of base; either of the two isomers was prepared in a highly selective way.

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