✦ LIBER ✦

Regioselective labelling of anilides with deuterium

✍ Scribed by W J S Lockley

Publisher: John Wiley and Sons
Year: 1985
Tongue: French
Weight: 298 KB
Volume: 22
Category: Article
ISSN: 0022-2135
DOI: 10.1002/jlcr.2580220612

No coin nor oath required. For personal study only.

✦ Synopsis

N-Aryl amides may be deuterated by exchange with deuterium oxide in the presence of rhodium(fI1) chloride. Under such conditions deuterium is introduced into positions t o the anilide nitrogen atom with a high degree of regioselectivity.

📜 SIMILAR VOLUMES

Regioselective syntheses of deuterium la

Regioselective syntheses of deuterium labelled 6-hydroxydopamines

✍ John Simmons; Ronald T. Borchardt 📂 Article 📅 1983 🏛 John Wiley and Sons 🌐 French ⚖ 373 KB

Convenient syntheses of 2,4-,a,a-and 5,B-deuterium labelled 6-hydroxydopamines have been developed. 2,4,5-Trimethoxybenzaldehyde (1) was reductively aminated to give 2,4,5-trimethoxybenzylamine (2). Quaternization of the amine with methyliodide followed by displacement with cyanide gave 2,4,5-trimet

Deuterium labelling of theaflavin

✍ Weimin Peng; Yin-fang Yao 📂 Article 📅 2009 🏛 John Wiley and Sons 🌐 French ⚖ 123 KB

## Abstract An efficient deuterium labelling of theaflavin, aiming at radiolabelling of theaflavin, was accomplished for the first time by using 4‐deuterium‐labelled __epi__‐catechin as the precursor and the resulting D‐labelled theaflavin was fully characterized by ^1^H NMR, ^13^C NMR, IR spectros

Regioselective synthesis of unsymmetrica

Regioselective synthesis of unsymmetrical deuterium labelled hydrazines and azoxy compounds

✍ Curt S. Cooper; Robert J. Weinkam 📂 Article 📅 1984 🏛 John Wiley and Sons 🌐 French ⚖ 454 KB

A method f o r t h e p r e p a r a t i o n o f deuterium l a b e l l e d unsymm e t r i c a l hydrazines was developed. This method was used t o prepare l-benzyl-2-methyl-\*H1-hydrazine hydrobromide and l-benzyl-zH~-2-methylhydrazine hydrobromide, analogs o f t h e cancer chemotheraputic agent proca

Regioselective deuterium labelling of ar

Regioselective deuterium labelling of aromatic acids, amides and amines using group VIII metal catalysts

✍ W J S Lockley 📂 Article 📅 1984 🏛 John Wiley and Sons 🌐 French ⚖ 468 KB

Regioselective deuterium labeling of 1,4

Regioselective deuterium labeling of 1,4-disubstituted-1,2,3,6-tetrahydropyridines

✍ Stéphane Mabic; John M. Rimoldi; Neal Castagnoli Jr. 📂 Article 📅 1997 🏛 John Wiley and Sons 🌐 French ⚖ 643 KB

Deuterium labelling of poly((dimethylimi

Deuterium labelling of poly((dimethyliminio)alkylenes)

✍ B. Westermark 📂 Article 📅 1988 🏛 John Wiley and Sons 🌐 French ⚖ 351 KB

Selectively deuterated monomers for preparation of deuterated po 1 y ( ( dime t h y 1 i m i n i o ) prop y 1 e ne ) , p o 1 y ( ( d i m e t h y 1 i 10 i n i 0 ) hex y 1 c n e ) , and poly((dimethy1iminio)decylene) have been synthesized:(2-'Y2)-1.3-dibromopropane. ( 1.10-11 2 ) -, ( 2 , 9-2H2 I-,