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Regional perfusion with hemofiltration (chemofiltration) for the treatment of patients with regionally advanced cancer

โœ Scribed by Mordechai Gutman; Subhi Abu-Abid; Patrick Sorkine; Moshe Inbar; Dina Lev; Zipora Chen; Dan Oron; Samario Chaitchik; Joseph M. Klausner


Publisher
John Wiley and Sons
Year
1996
Tongue
English
Weight
520 KB
Volume
78
Category
Article
ISSN
0008-543X

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โœฆ Synopsis


BACKGROUND.

Regionally advanced cancer is a common, often unresolved problem. Effective local control with chemotherapy is limited by the toxicity following systemic administration. Chemofiltration (CF) is a form of regional perfusion that enables the administration of cytotoxic drugs into one body area while limiting systemic toxicity. The drug is infused into the artery supplying the involved area. The venous effluent of the same organ is pumped out into a hemofiltration unit at a high flow rate. The drug is then filtered away and the blood returned to systemic circulation.


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