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Regional chromosomal assignment of the human mineralocorticoid receptor gene to 4q31.1

✍ Scribed by Norma Morrison; Stephen B. Harrap; Jeffrey L. Arriza; Elizabeth Boyd; J. Michael Connor

Publisher: Springer
Year: 1990
Tongue: English
Weight: 563 KB
Volume: 85
Category: Article
ISSN: 0340-6717
DOI: 10.1007/bf00276340

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✦ Synopsis

The gene for human mineralocorticoid receptor (hMR), previously mapped to chromosome 4, has been further localized to 4q31.1 by in situ hybridization using a biotinylated 3.75 kb human cDNA clone encoding the primary amino acid sequence of hMR as a probe. Preliminary comparative mapping studies in orangutan (Pongo pygmaeus) suggest localization of the probe to the long arm of chromosome 3.

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