Human phosphofructokinase (PFK; EC 2.7.1.11) is under the control of three structural loci which encode muscle-type (M), liver-type (L), and platelet or fibroblast-type (P) subunits; human diploid fibroblasts and leukocytes express all three loci. In order to assign the human PFKP locus to a specifi
Regional chromosomal assignment of the human platelet phosphofructokinase gene to 10p15
โ Scribed by Norma Morrison; Craig Simpson; Linda Fothergill-Gilmore; Elizabeth Boyd; J. Michael Connor
- Publisher
- Springer
- Year
- 1992
- Tongue
- English
- Weight
- 122 KB
- Volume
- 89
- Category
- Article
- ISSN
- 0340-6717
No coin nor oath required. For personal study only.
โฆ Synopsis
A cDNA for human platelet 6-phosphofructokinase (PFKP) has been isolated from a human Raji cell line cDNA library. Using this cDNA as a probe, the gene for human PFKP, previously mapped to chromosome 10pter-p11.1, has been further localized to 10p15 by non-isotopic in situ hybridization.
๐ SIMILAR VOLUMES
The gene for human mineralocorticoid receptor (hMR), previously mapped to chromosome 4, has been further localized to 4q31.1 by in situ hybridization using a biotinylated 3.75 kb human cDNA clone encoding the primary amino acid sequence of hMR as a probe. Preliminary comparative mapping studies in o
Segregation analysis of human-mouse somatic cell hybrids involving fibroblasts of a 10/17 translocation carrier as human partner allowed to assign the gene for human soluble GOT to 10q24 leads to qter.