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Regiochemistry in radical cyclizations (5-endo versus 4-exo) of N-(2-phenylthio- and 2-phenylcyclohex-1-enyl)-α-halo amides

✍ Scribed by Hiroyuki Ishibashi; Kazuya Kodama; Masahiro Higuchi; Osamu Muraoka; Genzoh Tanabe; Yoshifumi Takeda


Book ID
108371334
Publisher
Elsevier Science
Year
2001
Tongue
French
Weight
211 KB
Volume
57
Category
Article
ISSN
0040-4020

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ChemInform Abstract: Effect of Temperatu
✍ H. ISHIBASHI; M. HIGUCHI; M. OHBA; M. IKEDA 📂 Article 📅 2010 🏛 John Wiley and Sons ⚖ 34 KB 👁 2 views

Effect of Temperature on 5-endo-and 4-exo-trig Radical Cyclizations of N-Vinylic α-Halo Amides. -The reaction course is found to depend on the temperature. The method provides a new entry to tetrahydroindoles as versatile synthetic intermediates.