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ChemInform Abstract: Regiochemistry in Aryl Radical Cyclizations (5-exo versus 6-endo) of N-Vinylic 2-Iodobenzamides.

✍ Scribed by Hiroyuki Ishibashi; Kohei Ohata; Michiyo Niihara; Tatsunori Sato; Masazumi Ikeda


Publisher
John Wiley and Sons
Year
2010
Weight
32 KB
Volume
31
Category
Article
ISSN
0931-7597

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Effect of Temperature on 5-endo-and 4-exo-trig Radical Cyclizations of N-Vinylic Ξ±-Halo Amides. -The reaction course is found to depend on the temperature. The method provides a new entry to tetrahydroindoles as versatile synthetic intermediates.