Regio- and selective synthesis of 4,6-disubstituted-2-pyridones

✍ Scribed by Khalil Cherry; Mohamed Abarbri; Jean-Luc Parrain; Alain Duchêne

• Book ID: 104254066
• Publisher: Elsevier Science
• Year: 2003
• Tongue: French
• Weight: 229 KB
• Volume: 44
• Category: Article
• ISSN: 0040-4039
• DOI: 10.1016/s0040-4039(03)01429-1

✦ Synopsis

Palladium catalysed regio-and stereoselective annulation of allenyl stannanes by b-iodo vinylic amides gives good yields of the corresponding 2-pyridones. This annulation probably occurs via a Stille reaction/cyclisation sequence.