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ChemInform Abstract: Synthesis of 2,4-Disubstituted N-Acyl-5,6-dihydro-2-pyridones.

✍ Scribed by D. L. COMINS; X. CHEN; S. P. JOSEPH

Publisher
John Wiley and Sons
Year
2010
Weight
30 KB
Volume
28
Category
Article
ISSN
0931-7597

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ChemInform Abstract: C-3 Acetoxylation o
ChemInform Abstract: C-3 Acetoxylation of N-Acyl-2,3-dihydro-4-pyridones.
✍ D. L. COMINS; D. A. STOLZE; P. THAKKER; C. L. MCARDLE πŸ“‚ Article πŸ“… 2010 πŸ› John Wiley and Sons βš– 28 KB πŸ‘ 1 views

C-3 Acetoxylation of N-Acyl-2,3-dihydro-4-pyridones. -Stereoselective C-3 acetoxylation of various N-acyldihydropyridones (I) is achieved under mild conditions using lead tetraacetate. The analogous reaction of the indolizidinone (IV) to the cis product proceeds with considerably lower yield.