✦ LIBER ✦

Reference distributions for serum iron and transferrin saturation: A comparison of a large cohort to the world's literature

✍ Scribed by Robert F. Ritchie; Glenn E. Palomaki; Louis M. Neveux; Olga Navolotskaia; Thomas B. Ledue; Wendy Y.Craig

Publisher: John Wiley and Sons
Year: 2002
Tongue: English
Weight: 122 KB
Volume: 16
Category: Article
ISSN: 0887-8013
DOI: 10.1002/jcla.10047

No coin nor oath required. For personal study only.

✦ Synopsis

Abstract

The appropriate clinical use of serum iron and transferrin saturation (TSAT) requires satisfactory reference intervals from birth to old age, and for males and females. This study identified 54 publications from 1974 to 2001 that met the criteria used in three prior meta‐analyses, and these were analyzed statistically. A summary of our review is presented along with our reference population data on these measurements. This analysis places previous publications in perspective and suggests possible reasons for the observed differences. Previous studies of the individual analytes, serum iron, transferrin, and TSAT values agree with the reference ranges presented in this study, although the entire experience over time and between sexes has not been available before. Our 95% reference ranges are somewhat broader than those of the smaller studies, but they agree well with those of the larger ones. J. Clin. Lab. Anal. 16:246–252, 2002. © 2002 Wiley‐Liss, Inc.

📜 SIMILAR VOLUMES

Reference distributions for α2-macroglob

Reference distributions for α2-macroglobulin: A comparison of a large cohort to the world's literature

✍ Robert F. Ritchie; Glenn E. Palomaki; Louis M. Neveux; Olga Navolotskaia 📂 Article 📅 2004 🏛 John Wiley and Sons 🌐 English ⚖ 79 KB

## Abstract The lack of satisfactory methods for quantifying serum levels and a credible reference material has limited bedside use of serum alpha~2~‐macroglobulin (α2M) measurements. Great strides have been made in the last few years. The remaining barrier to more relevant and cost effective use o

Reference distributions for serum iron a

Reference distributions for serum iron and transferrin saturation: a practical, simple, and clinically relevant approach in a large cohort

✍ Robert F. Ritchie; Glenn E. Palomaki; Louis M. Neveux; Olga Navolotskaia; Thomas 📂 Article 📅 2002 🏛 John Wiley and Sons 🌐 English ⚖ 170 KB

## Abstract The principal considerations driving iron status evaluation are clinical concern for anemia and the possibility of iron‐storage disease. Most often, the circulating levels of transferrin (or total iron binding capacity) and serum iron are measured and the percentage of transferrin satur

Reference distributions for the negative

Reference distributions for the negative acute-phase proteins, albumin, transferrin, and transthyretin: A comparison of a large cohort to the world's literature

✍ Robert F. Ritchie; Glenn E. Palomaki; Louis M. Neveux; Olga Navolotskaia 📂 Article 📅 1999 🏛 John Wiley and Sons 🌐 English ⚖ 110 KB 👁 1 views

Clinical interpretation of the acute-phase proteins-albumin, transferrin, and transthyretin-has been hampered by the lack of accurate and precise methods for quantifying the levels and a stable and respected reference material. Now that these issues have been addressed, the community is faced with t

Reference distributions for immunoglobul

Reference distributions for immunoglobulins A, G, and M: A comparison of a large cohort to the world's literature

✍ Robert F. Ritchie; Glenn E. Palomaki; Louis M. Neveux; Olga Navolotskaia 📂 Article 📅 1998 🏛 John Wiley and Sons 🌐 English ⚖ 81 KB 👁 1 views

Clinical interpretation of immunoglobulin measurements requires accurate and precise assays and widely accepted reference preparations, as well as reliable age- and gender-specific reference ranges. This last requirement, the topic of numerous publications, has not been addressed adequately. By a co

Reference distributions for complement p

Reference distributions for complement proteins C3 and C4: A comparison of a large cohort to the world's literature

✍ Robert F. Ritchie; Glenn E. Palomaki; Louis M. Neveux; Olga Navolotskaia 📂 Article 📅 2004 🏛 John Wiley and Sons 🌐 English ⚖ 86 KB

## Abstract The lack of credible reference materials and satisfactory methods for quantifying serum levels has limited the bedside use of complement protein (C3 and C4) measurements. However, great technological strides have been made in the last few years. The remaining barrier to a more relevant

Reference distributions for apolipoprote

Reference distributions for apolipoproteins AI and B and B/AI ratios: comparison of a large cohort to the world's literature

✍ Robert F. Ritchie; Glenn E. Palomaki; Louis M. Neveux; Thomas B. Ledue; Santica 📂 Article 📅 2006 🏛 John Wiley and Sons 🌐 English ⚖ 199 KB

## Abstract Limiting the clinical utility of apolipoproteins AI (apo AI) and B (apo B) and the apo B/AI ratios until the last decade has been the lack of satisfactory methods for quantifying serum levels and credible reference materials. Great technological strides have been made in the last few ye