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Reed–Sternberg-like cells of ALK-positive anaplastic large cell lymphoma with near-tetraploidy

✍ Scribed by Katsuya Yamamoto; Kimikazu Yakushijin; Yumiko Inui; Atsuo Okamura; Yoshitake Hayashi; Hiroshi Matsuoka; Hironobu Minami


Book ID
114795675
Publisher
John Wiley and Sons
Year
2012
Tongue
English
Weight
157 KB
Volume
88
Category
Article
ISSN
0902-4441

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Anaplastic large cell lymphoma (ALCL) comprises a group of non-Hodgkin lymphomas characterized by the expression of the CD30/Ki-1 antigen. A subset of ALCL is characterized by chromosomal translocations involving the anaplastic lymphoma kinase (ALK) gene on chromosome 2. While the most common transl