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ALK-positive anaplastic large cell lymphoma with TPM3-ALK translocation

✍ Scribed by Saeam Shin; Juwon Kim; Sun Och Yoon; Yu Ri Kim; Kyung-A. Lee


Book ID
113773729
Publisher
Elsevier Science
Year
2012
Tongue
English
Weight
470 KB
Volume
36
Category
Article
ISSN
0145-2126

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Anaplastic large cell lymphoma (ALCL) comprises a group of non-Hodgkin lymphomas characterized by the expression of the CD30/Ki-1 antigen. A subset of ALCL is characterized by chromosomal translocations involving the anaplastic lymphoma kinase (ALK) gene on chromosome 2. While the most common transl