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Gastrointestinal: Gastroduodenal involvement of ALK-positive anaplastic large cell lymphoma

โœ Scribed by H Ishii; H Isomoto; H Taniguchi; N Kinoshita; K Matsushima; J Taguchi; Y Miyazaki; K Nakao


Book ID
108954086
Publisher
John Wiley and Sons
Year
2011
Tongue
English
Weight
435 KB
Volume
26
Category
Article
ISSN
0815-9319

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Anaplastic large cell lymphoma (ALCL) comprises a group of non-Hodgkin lymphomas characterized by the expression of the CD30/Ki-1 antigen. A subset of ALCL is characterized by chromosomal translocations involving the anaplastic lymphoma kinase (ALK) gene on chromosome 2. While the most common transl

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Background. There is great diversity in the clinical presentation of CD30 (Ki-1)-positive, anaplastic large cell lymphoma (ALCL). The authors report two patients in whom the clinical and morphologic features mimicked gastrointestinal carcinoma. Methods. Surgical pathology specimens were examined us