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Reduction of platelet thromboxane A2 production ex vivo and in vivo by clopidogrel therapy

✍ Scribed by P. C. J. ARMSTRONG; A.-R. A. DHANJI; A. T. TUCKER; J. A. MITCHELL; T. D. WARNER

Book ID
109153193
Publisher
John Wiley and Sons
Year
2009
Tongue
English
Weight
155 KB
Volume
8
Category
Article
ISSN
1538-7933

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Picotamide (G 137), a new non prostanoid inhibitor of in vitro arachidonic acid induced platelet aggregation, has been further characterized in in vitro and ex vivo studies. When whole blood was activated with collagen in the presence of picotamide 5 x 10(-4) M, thromboxane B2 production was decreas