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Inhibition by picotamide of thromboxane production in vitro and ex vivo

✍ Scribed by F. Violi; A. Ghiselli; L. Iuliano; D. Praticò; C. Alessandri; F. Balsano

Publisher
Springer
Year
1988
Tongue
English
Weight
376 KB
Volume
33
Category
Article
ISSN
0031-6970

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Picotamide (G 137), a new non prostanoid inhibitor of in vitro arachidonic acid induced platelet aggregation, has been further characterized in in vitro and ex vivo studies. When whole blood was activated with collagen in the presence of picotamide 5 x 10(-4) M, thromboxane B2 production was decreas