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Reduction of photohemolytic activity of benoxaprofen byβ-cyclodextrin complexations

✍ Scribed by Teruhiko Hoshino; Kazuhisa Ishida; Tetsumi Irie; Fumitoshi Hirayama; Kaneto Uekama; Masaki Yamasaki


Book ID
104869205
Publisher
Springer Netherlands
Year
1988
Tongue
English
Weight
452 KB
Volume
6
Category
Article
ISSN
0923-0750

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Reduction of bitterness of antihistamini
✍ Nao Ono; Yuji Miyamoto; Takako Ishiguro; Keiichi Motoyama; Fumitoshi Hirayama; D 📂 Article 📅 2011 🏛 John Wiley and Sons 🌐 English ⚖ 546 KB

Reduction of bitterness of antihistaminic drugs by cyclodextrin (CyD) complexation was examined. The stability constant (Kc) of the 1:1 CyD inclusion complexes with antihistaminic drugs increased in the order of 2-hydroxypropyl-β-CyD (HP-β-CyD) ≈ β-CyD > γ-CyD > α-CyD for diphenhydramine and epinast