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Reduction in the ulcerogenicity of naproxen by complexation with β-cyclodextrin

✍ Scribed by F.J.Otero Espinar; S.Anguiano Igea; J.Blanco Méndez; J.L.Vila Jato

Book ID
113365390
Publisher
Elsevier Science
Year
1991
Tongue
English
Weight
513 KB
Volume
70
Category
Article
ISSN
0378-5173

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Studies of the Naproxen:β-Cyclodextrin I
Studies of the Naproxen:β-Cyclodextrin Inclusion Complex
✍ J. Wang; I.M. Warner 📂 Article 📅 1993 🏛 Elsevier Science 🌐 English ⚖ 413 KB

The interaction of a nonsteroidal anti-inflammatory drug, naproxen, with \(\beta\)-CD has been studied by several analytical techniques, including 1-D and 2-D proton NMR, fluorescence spectroscopy, and FAB-MS. The negative ion FAB-MS confirmed the existence of a 1:1 inclusion complex of naproxen and