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Reduction of estradiol 3-methyl ether by lithium and gaseous ammonia

โœ Scribed by James F. Fisher; Leland L. Smith


Book ID
118977422
Publisher
Elsevier Science
Year
1967
Tongue
English
Weight
302 KB
Volume
9
Category
Article
ISSN
0039-128X

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The 500 MHz 'H spectra of the 3-methyl ethers of estrone, estradiol and their 14a-methyl analogues were assigned by proton decoupling and analysed by second-order calculations for chemical shifts and coupling constants. Introduction of a 14a-Me group effects consistent deshielding of 1,3 diaxially d